The Travails of Major Depression and Zoloft

The Travails of Major Depression and Zoloft

Pfizer Inc., which is the world’s biggest pharmaceutical company, manufactured one of the most prescribed antidepressant in the United States-Zoloft. Zoloft is the medical treatment for major depression, which affects more than 19 million adults in the United States, including other neurologic disorders. Taking the drug, however, entails much consideration due to the side effects of Zoloft.

Major depressive disorder is a syndrome – group of symptoms – characterizing a sad and/or irritable mood which is no longer the usual sadness or grief. The sadness of depression, in particular, is more intense and longer in duration that it interferes with everyday life.

The symptoms of depression may include but are not limited to:

– Difficulty concentration, remembering details, and making decisions

– Fatigue and decreased energy

– Feelings of guilt, worthlessness, and/or hopelessness

– Feelings of pessimism

– Insomnia, early-morning wakefulness, or excessive sleeping

– Irritability, restlessness

– Loss of interest in activities or hobbies once pleasurable, including sex

– Increase or loss in appetite

– Persistent aches or pains, headaches, cramps, or digestive problems unrelieved with treatment

– Persistent sadness, anxiety or “empty” feelings

– Suicidal thoughts and/or suicide attempts

Feeling sad, lonely or depressed at times is definitely normal to anyone especially as a reaction to loss, struggles in life, or a fractioned self-esteem. However, when it adversely affects your family, work or school life, sleeping and eating habits, and general health, then you might already need the help of medical professionals.

Symptoms of major depression should not be taken lightly as it may go from bad to worse if left untreated and may cause life-threatening actions. At least one out of ten people with major depressive disorder ended their own life.

Antidepressants are often the first treatment for people with depression. The most common class of antidepressants is SSRIs or selective serotonin reuptake inhibitors. This type of antidepressant includes Zoloft which is also known by its generic name sertraline hydrochloride.

SSRIs work on the neurotransmitter serotonin which is important for the communication between brain cells. Several conditions which include depression may develop as levels of serotonin dwindle. Zoloft blocks serotonin absorption to make sure that there is enough serotonin for the transmission of chemical signals.

Finding out if you have major depression requires the help of your health care provider. Moreover, taking Zoloft should be consulted first due to the risks involved in taking the drug. Major depression is a serious illness and likewise treatment must also be taken seriously.


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